Klebsiella Oxytoca: Causes, Symptoms, and How to Prevent It

Klebsiella Oxytoca: Causes, Symptoms, and How to Prevent It
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Tripboba.com - Klebsiella oxytoca is a pathogenic bacterium, gram-negative rod (bacilli), opportunistic pathogen, non-motile bacterium, based on its need for oxygen. Klebsiella pneumonia is a facultative anaerobic bacterium.

Klebsiella oxytoca can ferment lactose. In tests with indole, Klebsiella pneumonia will show negative results. Klebsiella pneumonia can reduce nitrate.

Klebsiella oxytoca is commonly found in the mouth, skin, and gastrointestinal tract, but the natural habitat of Klebsiella pneumonia is in the soil, has a large polysaccharide deposit, usually a positive result on the lysine and citrate decarboxylase tests and is included in Enterobacteriaceae.

Diseases caused by these bacteria include infectious diseases such as the urinary tract, septicemias and bronchopneumonia tissue infections, and gram-negative bacterial pneumonia.

What is Klebsiella Oxytoca

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Klebsiella oxytoca is found in the airways and feces about 5% of normal people and can cause pneumonia bacteria. Klebsiella oxytoca can cause extensive consolidation with hemorrhagic necrosis in the lungs.

Klebsiella sometimes causes urinary tract infections and bacteremia with focal lesions in weak patients. Klebsiella oxytoca is also an opportunistic pathogen for patients with chronic lung disease and rhinoscleroma.

The main disease caused by this bacterium is pneumonia. Klebsiella oxytoca can cause disease because it has two types of antigens on its cell surface: O antigens. O antigens are lipopolysaccharides found in nine varieties.

Antigen K is a polysaccharide surrounded by capsules with more than 80 varieties. Both of these antigens increase the pathogenicity of Klebsiella oxytoca. In addition, Klebsiella pneumonia is able to produce the enzyme ESBL (Extended Spectrum Beta Lactamase) which can paralyze the work of various types of antibiotics.

This can cause bacteria to become resistant and be difficult to disable. Resistance to these antibiotics by (1) Inactivation drugs by enzymes degradation or modification such as beta lactamaces and vaminoglycosides transferases, (2) Changes in target drugs (3) The emergence of a bypass pathway that is not inhibited by the drug (4) Reducing membrane permeability for the drug ( 5) Drugs from cells.

Klebsiella Oxytoca Causes

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Klebsiella oxytoca infection occurs when this bacteria enters the lungs, Klebsiella pneumoniae bacteria can enter the body when consuming vegetables that have not been washed or drink contaminated water.

Klebsiella oxytoca infection often occurs in patients suffering from other diseases such as diabetes, chronic lung disease, or chronic alcoholics. Klebsiella oxytoca infection is mostly a nosocomial infection that occurs in hospitalized patients whose immune system is weak.

Klebsiella Oxytoca Symptoms You Should Know

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After Klebsiella oxytoca enters the lungs, this bacteria causes a lot of damage to the lungs. Klebsiella pneumoniae bacteria causes necrosis, inflammation, and bleeding in lung tissue.

  • This condition causes the production of very thick mucus, called sputum jelly raisins (currant jelly sputum). Rapid lung tissue damage is a distinguishing factor (specific characteristic) of Klebsiella oxytoca infection.
  • The initial symptom of Klebsiella oxytoca infection is a sudden high fever, this fever can reach a temperature of more than 39.5 °C accompanied by other symptoms such as chills and dizziness.
  • The patient will also experience a cough with phlegm where the phlegm is thick mucus and sometimes accompanied by blood, if the condition gets worse it will lead to abscess formation. Abscesses are bags of dead tissue that contain millions of bacteria Klebsiella oxytoca.
  • Abscess formation causes the lungs can not expand because it is blocked by the presence of connective tissue around, this condition can cause the lungs to collapse and the infection will spread to the upper respiratory tract.
  • When the infection spreads, the airway becomes increasingly obstructed and causes foul-smelling nasal discharge.

Here are some of the symptoms of Klebsiella oxytoca infection:

  • Cough
  • Sputum which is brown or blood phlegm
  • Respiratory problems
  • High fever
  • Weak
  • Shivering
  • Chest pain
  • Nausea
  • Foul-smelling nasal discharge
  • Headache
  • Chest tightness
  • Wheezing
  • Cyanosis (blue lips and nails)
  • Confusion
  • Treatment

Klebsiella Oxytoca Treatment You Can Do

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Treating infections due to Klebsiella oxytoca is very difficult because it is often a nosocomial infection and this bacterium is very resistant to antibiotics and drugs. Treatment of Klebsiella oxytoca infection involves the use of antibiotics such as aminoglycosides and cephalosporins.

Many patients show a good response to third-generation drugs such as amikacin, tobramycin, clavulanate, aztreonam, gentamicin, and others. The death rate due to infection with Klebsiella oxytoca is very high, even after the patient receives proper treatment.

Therefore, it is important to know and understand the symptoms of Klebsiella oxytoca infection. Early treatment will help prevent fatal conditions from this disease.

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